Generation of two human iPSC lines with Exon 3 mutations in BCL2-Associated Athanogene 3 (BAG3) from dilated cardiomyopathy patients

Dilated cardiomyopathies (DCM) are one of the main causes of heart failure as one ages.BAG3 is a chaperone protein that is heavily implicated in the development of DCM and speed of progression toward heart failure.Here we generate two human iPSC Sewing Machine Accessories lines from individuals with mutations in exon 3 of BAG3 and provide validatio

read more